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KMID : 0377619750280020237
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Korean Jungang Medical Journal
1975 Volume.28 No. 2 p.237 ~ p.243
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A Clinical Observation of Kelodin and Kefacin
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Abstract
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There are many antibiotics for the treatment of infections, however, their effectiveness decreasing as the development of microorganisims became risistant to them.
In recently, we had an approtunity to use 2 new antibiotics, which are known to be effective on gram positive and negative microorganisms and spirochetes.
We were administered the two knew antibiotics, kelodin and kefacin on 10 postoperative infections, 5 recurrent urinary infections in spinal cord injuries and 5 operative cases prophylactically. Administered dosage was 500mg every 6 hours, intravenously intramuscularly or orally, and 20mg/kg/day for children and for a duration of 10?14 days.
They were effective in 8 patients of 10 postoperative infected cases, all in urinary tract infections and prophylactic cases. They were no response on 2 in 3 pseudomonas infections.
One patient complained of local pain on injected site, but no serious side effects were found in the other patients.
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